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Chloride intracellular channel 4

Cat. No.: CBCRY20
Background: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Protein Classification: Transport protein
Structure Weight: 89641.50 Da
Polymer: 1
Molecule: Chloride intracellular channel protein 4
Chain Length: 261 amino acids
PDB ID: 2D2Z
MMDB ID: 39169
Source: E.coli
Method: X-Ray Diffraction
Resolution: 2.8Å
Reference: Li, Y.F., Li, D.F., Zeng, Z.H., Wang, D.C. (2006) Trimeric structure of the wild soluble chloride intracellular ion channel CLIC4 observed in crystals Biochem.Biophys.Res.Commun. 343: 1272-1278
Gene Name: CLIC4
Synonyms: CLIC4L; DKFZp566G223; FLJ38640; H1; MTCLIC; huH1; p64H1; OTTHUMP00000003380; chloride intracellular channel 4 like; Intracellular chloride ion channel protein p64H1
UniProt ID: Q9Y696
Gene ID: 25932
Chromosome Location: 1p36.11
Function: chloride ion binding; protein binding; voltage-gated chloride channel activity; voltage-gated ion channel activity.

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