Diamine Acetyltransferase 1 CBCRY21

Diamine Acetyltransferase 1

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Diamine Acetyltransferase 1

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Cat. No. : CBCRY21
Background : Spermidine/spermine N(1)-acetyltransferase (SSAT; EC 2.3.1.57) is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the N(1)-acetylation of spermidine and spermine and, by the successive activity of polyamine oxidase, spermine can be converted to spermidine and spermidine to putrescine.
Protein Classification : Transferase
Structure Weight : 42238.60 Da
Polymer : 1
Molecule : Diamine acetyltransferase 1
Chain Length : 179 amino acids
PDB ID : 2G3T
MMDB ID : 38382
Source : E.coli
Method : X-Ray Diffraction
Resolution : 1.8Å
Reference : Zhu, Y.Q., Zhu, D.Y., Yin, L., Zhang, Y., Vonrhein, C., Wang, D.C. (2006) Crystal structure of human spermidine/spermine N1-acetyltransferase (hSSAT): the first structure of a new sequence family of transferase homologous superfamily Proteins 63: 1127-1131
Gene Name : SAT1
Synonyms : DC21; EC 2.3.1.57; KFSD; SAT; SSAT; SSAT-1;OTTHUMP00000023061; diamine N-acetyltransferase 1; diamine acetyltransferase 1; spermidine/spermine N1-acetyltransferase alpha; spermidine/spermine N1-acetyltransferase 1; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase
UniProt ID : P21673
Gene ID : 6303
Chromosome Location : Xp22.1
Function : acyltransferase activity; diamine N-acetyltransferase activity; transferase activity

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