"NF1" Related Products

Recombinant Human Neurofibromin 1

Cat. No.: NF1-334H
Description: The NF1 (Neurofibromin) gene product acts as a GTPase activating factor (GAP) on Ras. Inactivating mutations in NF1 lead to neurofibromatosis type 1. NF1- 333 contains residues 1198-1530 of human NF1 comprising the functional GAP-related domain that is able to stimulate GTP-hydrolysis on wild type Ras. MW = 36.6 kDa (333 amino acids).
Source: E. coli.
Form: Liquid. Supplied in 50 mM Tris-HCl pH 7.5, 5 mM MgCl2 and 3 mM DTE.
Purity: > 95% by SDS-PAGE.
Usage: For in vitro use only.
Storage: Quality guaranteed for 12 months store at -80°C. Avoid freeze / thaw cycles.
Gene Name: NF1 neurofibromin 1 [ Homo sapiens ]
Synonyms: NF1; neurofibromin 1; WSS; NFNS; VRNF; FLJ21220; DKFZp686J1293;neurofibromin; neurofibromatosis; Recklinghausen disease; Watson disease; Neurofibromatosis-related protein NF-1;Neurofibromin truncated
Gene ID: 4763
mRNA Refseq: NM_000267
Protein Refseq: NP_000258
MIM: 162200
UniProt ID: P21359
Chromosome Location: 17q11.2
Pathway: MAPK signaling pathway
Function: Ras GTPase activator activity; protein binding
Products Types ◆ Recombinant Protein

Research Area Cancer Metabolism Proteins
Related Gene

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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