"NF1" Related Products

Recombinant Human Neurofibromin 1

Cat. No. : NF1-334H
Description : The NF1 (Neurofibromin) gene product acts as a GTPase activating factor (GAP) on Ras. Inactivating mutations in NF1 lead to neurofibromatosis type 1. NF1- 333 contains residues 1198-1530 of human NF1 comprising the functional GAP-related domain that is able to stimulate GTP-hydrolysis on wild type Ras. MW = 36.6 kDa (333 amino acids).
Source : E. coli.
Form : Liquid. Supplied in 50 mM Tris-HCl pH 7.5, 5 mM MgCl2 and 3 mM DTE.
Purity : > 95% by SDS-PAGE.
Usage : For in vitro use only.
Storage : Quality guaranteed for 12 months store at -80°C. Avoid freeze / thaw cycles.
PDB rendering based on 1nf1. :

Gene Name : NF1 neurofibromin 1 [ Homo sapiens ]
Synonyms : NF1; neurofibromin 1; WSS; NFNS; VRNF; FLJ21220; DKFZp686J1293;neurofibromin; neurofibromatosis; Recklinghausen disease; Watson disease; Neurofibromatosis-related protein NF-1;Neurofibromin truncated
Gene ID : 4763
mRNA Refseq : NM_000267
Protein Refseq : NP_000258
MIM : 162200
UniProt ID : P21359
Chromosome Location : 17q11.2
Pathway : MAPK signaling pathway
Function : Ras GTPase activator activity; protein binding

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