"Pggt1b" Related Products

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Recombinant Rat Protein Geranylgeranyltransferase Type I, Beta Subunit

Cat. No.: Pggt1b-324R
Description: GGTase-I (Geranylgeranyltransferase-I) catalyzes the transfer of the farnesyl and geranylgeranyl groups from farnesyl and geranylgeranyl-diphosphate to proteins ontaining a C-terminal CaaX motif, where 'C' is a conserved cysteine that is the site of farnesyl modification, 'a' is usually an aliphatic amino acid, and 'X' is leucine or phenylalanine. Farnesyltransferase (FT) and GGTase-I are closely related, sharing a common subunit and 30% identity in their β subunits.
Source: E. coli.
Form: Liquid. Supplied in 25 mM HEPES, pH 7.2, 25 mM NaCl and 5 mM DTT.
Purity: > 90% by SDS-PAGE.
Activity: 1 pmol of GGTase-I will transfer 5 pmol of Farnesyl to RhoA in 15 min at 37°C.
Usage: For in vitro use only.
Storage: Quality guaranteed for 12 months store at - 80°C. Avoid freeze / thaw cycles.
Gene Name: Pggt1b protein geranylgeranyltransferase type I, beta subunit [ Rattus norvegicus ]
Synonyms: Pggt1b; protein geranylgeranyltransferase type I, beta subunit; geranylgeranyltransferase type 1 beta; geranylgeranyltransferase type I (GGTase-I)
Gene ID: 81746
mRNA Refseq: NM_031082
Protein Refseq: NP_112344
UniProt ID: P53610
Chromosome Location: q11
Function: CAAX-protein geranylgeranyltransferase activity; drug binding; isoprenoid binding; metal ion binding; peptide binding; prenyltransferase activity; protein binding; transferase activity; zinc ion binding

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