|Cat. No. :
||Protein Tyrosin Phosphatase, catalytic domain. Protein Tyrosine Phosphatase- Basophil-like (PTP-BL)is a large nonreceptor type protein tyrosine phosphatase characterized by the presence of a extreme N-terminal KIND domain (kinase noncatalytic C-lobe domain, a protein module identified recently that shows homology to the regulatory C-lobe of protein kinases but that lacks catalytic activity), a N-terminal FERM domain (four point one, ezrin, radixin, moesin homology domain), five PDZ (postsynaptic density protein-95, discs large, zonula occludens) regions and a C-terminal catalytically active domain. Current data suggest that PTP-BL is involved in regulation of cytoskeleton and of intracellular vesicular transport processes.
||For in vitro use only.
||Liquid. Supplied in 20 mM Tris-HCl pH 8.0, 100 mM KCl, 0.2 mM EDTA, 1 mM DTT and 20% glycerol.
||11 μmol/min/mg determined with pNPP as substrate at pH 7.4 and 37℃.
||> 95% by SDS-PAGE.
||Quality guaranteed for 12 months, store at -80℃. Avoid freeze / thaw cycles.
|PDB rendering based on 1d5g. :