Vacuolar Protein Sorting Protein 29 CBCRY38

Vacuolar Protein Sorting Protein 29

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Vacuolar Protein Sorting Protein 29

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Cat. No. : CBCRY38
Background : VPS29 belongs to a group of genes coding for vacuolar protein sorting (VPS) proteins that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene, Vps29, is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. Vps29 may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment.
Protein Classification : cytoplasmic protein
Structure Weight : 20531.90 Da
Polymer : 1
Molecule : Vacuolar Protein Sorting Protein 29
Chain Length : 182 amino acids
PDB ID : 1W24
MMDB ID : 32322
Source : E.coli
Method : X-Ray Diffraction
Resolution : 2.10Å
Reference : Wang, D., Guo, M., Liang, Z., Fan, J., Zhu, Z., Zang, J., Zhu, Z., Li, X., Teng, M., Niu, L., Dong, Y., Liu, P. (2005) Crystal Structure of Human Vacuolar Protein Sorting Protein 29 Reveals a Phosphodiesterase/Nuclease-Like Fold and Two Protein-Protein Interaction Sites. J.Biol.Chem. 280: 22962
Gene Name : VPS29
Synonyms : DC15; DC7; DKFZp564F0223; FLJ20492; PEP11; retromer protein; vacuolar protein sorting 29; vacuolar sorting protein VPS29/PEP11; x 007 protein; EC 3.1.3.3; hVPS29; vesicle protein sorting 29
UniProt ID : Q9UBQ0
Gene ID : 51699
Chromosome Location : 12q24
Function : zinc ion binding; hydrolase activity; metal ion binding

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