"Epha1" Related Products


Recombinant Mouse Epha1, GST-tagged, Active

Cat. No.: Epha1-299M
Product Overview: Recombinant mouseEpha1 (569-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MW=71 kDa.
Description: Epha1 is a member of the Eph family of receptor tyrosine kinases that have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the Eph subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. EPHA1 seems to be a marker of the differentiated normal epidermis and its downregulation in nonmelanoma skin cancer may contribute to carcinogenesis of these very frequent human tumors. EPHA1 represents a new potential prognostic marker and therapeutic target in nonmelanoma skin cancer.
Source: Sf9 insect cellsusing baculovirus.
Sequence: 569-end.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: Epha1 Eph receptor A1 [ Mus musculus ]
Synonyms: Epha1; Eph receptor A1; Eph; Esk; AL033318; 5730453L17Rik; ephrin receptor EphA1; EC
Gene ID: 13835
mRNA Refseq: NM_023580
Protein Refseq: NP_076069
UniProt ID: Q60750
Chromosome Location: 6 B2.1
Pathway: Axon guidance
Function: ATP binding; ephrin receptor activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity

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