"EPHB4" Related Products

Expand

Recombinant Human EPH Receptor B4, GST-tagged, Active

Cat. No. : EPHB4-306H
Product Overview : Recombinant human EPHB4 (561-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=50kDa.
Description : EPHB4 is a member of the Eph family of receptor tyrosine kinases which play a role in regulating cell adhesion and cell movement during embryonic development. Furthermore, because tissue disorganization and abnormal cell adhesion, movement, and survival characterize the more advanced stages of cancer, the inappropriate functioning of Eph receptor could play a causal role in malignancy. EPHB4 is uniquely expressed in the vascular endothelial and endocardial cells and animal knockout studies with EPHB4 reveal a phenotype that is similar to Ephrin B2 gene knockdown. Furthermore, EPHB4 has been shown to be the major essential interaction partner of Ephrin B2 in angiogenesis.
Source : Sf9 insect cellsusing baculovirus.
Sequence : 561-end.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : EPHB4 EPH receptor B4 [ Homo sapiens ]
Synonyms : EPHB4; EPH receptor B4; HTK; MYK1; TYRO11; ephrin receptor EphB4; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; hepatoma transmembrane kinase; EC 2.7.10.1; Tyro11; Ephrin type-B receptor 4; Tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase TYRO11; EPH receptor B4; Tyrosine-protein kinase receptor HTK; ephrin receptor EphB4; hepatoma transmembrane kinase
Gene ID : 2050
mRNA Refseq : NM_004444
Protein Refseq : NP_004435
MIM : 600011
UniProt ID : P54760
Chromosome Location : 7q22
Pathway : Axon guidance
Function : ATP binding; ephrin receptor activity; nucleotide binding; protein binding; receptor activity; transferase activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.