"MAPK3" Related Products

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Recombinant Human Mitogen-activated Protein Kinase 3, Active

Cat. No.: MAPK3-307H
Product Overview: Recombinant full-length, tag-free human ERK1 was expressed by baculovirus inSf9 insect cells. MW=44kDa.
Description: ERK1 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK1 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK1 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK1 translocates into the nucleus where it phosphorylates various transcription factors.
Source: Sf9 insect cellsusing baculovirus.
Sequence: Full-length.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: MAPK3 mitogen-activated protein kinase 3 [ Homo sapiens ]
Synonyms: MAPK3; mitogen-activated protein kinase 3; ERK1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; MGC20180;EC 2.7.11.24; Extracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase 1; Microtubule-associated protein 2 kinas; OTTHUMP00000174538; OTTHUMP00000174540; Microtubule-associated protein 2 kinase
Gene ID: 5595
mRNA Refseq: NM_001040056
Protein Refseq: NP_001035145
MIM: 601795
UniProt ID: P27361
Pathway: Acute myeloid leukemia; Adherens junction; Alzheimer"s disease; Alzheimer"s disease; B cell receptor signaling pathway; Bladder cancer; Chronic myeloid leukemia; Chemokine signaling pathway; Colorectal cancer; Dorso-ventral axis formation; Endometrial cancer; ErbB signaling pathway; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Gap junction; Glioma; GnRH signaling pathway; Insulin signaling pathway; Long-term potentiation; Long-term depression; MAPK signaling pathway; Melanogenesis; Melanoma; Natural killer cell mediated cytotoxicity; Neurotrophin signaling pathway; Non-small cell lung cancer; Pancreatic cancer; Pathways in cancer; Prion diseases; Regulation of actin cytoskeleton; Renal cell carcinoma; Renal cell carcinoma; T cell receptor signaling pathway; TGF-beta signaling pathway
Function: ATP binding; MAP kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

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