Recombinant Human FGR, GST-tagged, Active

• Cat.No.: FGR-317H
• Product Overview: Recombinant full-length human FGR was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW=86kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: FGR is a protooncogene that is a unique member of the tyrosine kinase gene family. Certain lymphomas (but not sarcomas or carcinomas) express FGR-related messenger RNA. This transcript is detected in Burkitt"s lymphoma cell lines naturally infected with Epstein-Barr virus (EBV), but not in EBV-negative Burkitt"s lymphoma cells. FGR expression is limited to normal peripheral blood granulocytes, monocytes, and alveolar macrophages, all of which contain 50 to 100 copies of c-fgr mRNA per cell.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog [ Homo sapiens ]
• Synonyms: FGR; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr; Proto-oncogene tyrosine-protein kinase FGR;EC2.7.10.2; P55-FGR
• Gene ID: 2268
• mRNA Refseq: NM_001042729
• Protein Refseq: NP_001036194
• UniProt ID: P09769
• Chromosome Location: 1p36.2-p36.1
• MIM: 164940
• Pathway: Chemokine signaling pathway
• Function: ATP binding; heparin binding; nucleotide binding; protein binding; transferase activity;non-membrane spanning protein tyrosine kinase activity