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Recombinant Human FGR, GST-tagged, Active

Cat. No.: FGR-317H
Product Overview: Recombinant full-length human FGR was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW=86kDa.
Description: FGR is a protooncogene that is a unique member of the tyrosine kinase gene family. Certain lymphomas (but not sarcomas or carcinomas) express FGR-related messenger RNA. This transcript is detected in Burkitt"s lymphoma cell lines naturally infected with Epstein-Barr virus (EBV), but not in EBV-negative Burkitt"s lymphoma cells. FGR expression is limited to normal peripheral blood granulocytes, monocytes, and alveolar macrophages, all of which contain 50 to 100 copies of c-fgr mRNA per cell.
Source: Sf9 insect cells using baculovirus.
Sequence: Full-length.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog [ Homo sapiens ]
Synonyms: FGR; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr; Proto-oncogene tyrosine-protein kinase FGR;EC2.7.10.2; P55-FGR
Gene ID: 2268
mRNA Refseq: NM_001042729
Protein Refseq: NP_001036194
UniProt ID: P09769
Chromosome Location: 1p36.2-p36.1
MIM: 164940
Pathway: Chemokine signaling pathway
Function: ATP binding; heparin binding; nucleotide binding; protein binding; transferase activity;non-membrane spanning protein tyrosine kinase activity

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