Recombinant Bovine Insulin-Like Growth Factor Binding Protein 2, 36kDa


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Recombinant Bovine Insulin-Like Growth Factor Binding Protein 2, 36kDa

IGFBP2 Related Products

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Cat. No. : IGFBP2-1414B
Product Overview : Recombinant bovine IGFBP-2 produced inCHO cellsis a 284 amino acid protein. MW = 30.776 kDa.
Description : Bovine Insulin-like Growth Factor Binding Protein-2 (bIGFBP-2) is one of the six “classical” IGF binding proteins that play an important role in stabilizing and regulating the activity of IGFs in vivo. bIGFBP-2 binds both human and bovine IGF-I and IGF-II and modifies their biological activity and bioavailability. The Animal/Media Grade product contains mature bovine IGFBP-2 of correct Molecular Weight as the major species. As a result of alternative processing by the CHO cells used for the bIGFBP-2 production, three other minor bIGFBP-2 isoforms are also present: 1) One with a three amino acid C-terminal deletion, denoted Des(1-3) bIGFBP-2. 2) One with a single amino acid N-terminal extension, denoted A-bIGFBP-2. 3) One with a four amino acid N-terminal extension, denoted GARA-bIGFBP-2.
Source : CHO cells.
Purity : >95% by HPLC and Mass Spectrometry.
Biological Activity : IGF-I Binding Assay : ED50 < 10 nM.
State And Appearance : Lyophilized white powder dried from 0.1% TFA / 30% acetonitrile and stored under dry nitrogen at a slight vacuum (-25 kPa).
Storage/Stability : At least 2 years at 2 - 4°C (lyophilized).
PDB rendering based on 2h7t. :

Gene Name : IGFBP2 insulin-like growth factor binding protein 2, 36kDa [ Bos taurus ]
Synonyms : insulin-like growth factor binding protein 2, 36kDa; IGFBP2
Gene ID : 282260
mRNA Refseq : NM_174555
Protein Refseq : NP_776980
UniProt ID : P13384
Chromosome Location : 2
Function : insulin-like growth factor I binding; insulin-like growth factor II binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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