"IGF1" Related Products

Expand
Expand

Recombinant Human Des(1-3)Insulin-like Growth Factor 1

Cat. No.: IGF1-325H
Product Overview: Recombinant Human Des(1-3)Insulin-like Growth Factor1 (IGF1) was produced recombinantly.
Description: Human Des(1-3)Insulin-like Growth Factor 1 (IGF1) is a 67 amino acid analog of human IGF-I lacking the N-terminal tripeptide Gly-Pro-Glu. Human Des(1-3)IGF1 is more potent than IGF1 in vitro and in vivo. This increased potency is due to reduced binding of human Des(1-3)IGF1 to most of the IGF binding proteins which normally inhibit the biological actions of IGF1. Human Des(1-3)IGF1 binds to the Type 1 IGF receptor with similar affinity to full length IGF1. This is a high quality reagent for use in studies on cell growth, IGF receptors and IGFBPs.
Source: Produced recombinantly.
Purity: >95 % (by HPLC and N-terminal sequence analysis).
Molecular Weight: 7365 daltons – confirmed by Mass Spectrometry.
N-terminal Sequence Analysis: 5 residues > 95 % single sequence.
Activity: Type 1 IGF receptor binding assay: ED50< 10 ng/ml. IGF binding protein assay: ED50 > 100 ng/ml. Stimulation of protein synthesis in rat L6 myoblasts: ED50 < 10 ng/ml.
Endotoxin: <0.1 EU/µg.
State And Appearance: Lyophilized white powder. Dried from 0.1 M acetic acid and stored under dry nitrogen at a slight vacuum (-25 kPa).
Storage: At least 2 years at 2 – 4℃ (lyophilized).
Gene Name: IGF1 insulin-like growth factor 1 (somatomedin C) [ Homo sapiens ]
Synonyms: IBP1; IGF-I; IGF-IA; IGFI; MGF; Somatomedin-C; Mechano growth factor; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); somatomedin C; IGF1B_HUMAN; Insulin-like growth factor IB [Precursor]; IGF-IB.
Gene ID: 3479
mRNA Refseq: NM_000618
Protein Refseq: NP_000609
MIM: 608747
UniProt ID: P01343
Chromosome Location: 12q23.2
Pathway: Focal adhesion; Glioma; Long-term depression; Melanoma; Prostate cancer; mTOR signaling pathway; Hemostasis
Function: Growth factor activity; Hormone activity; Hormone activity; Insulin receptor binding; Insulin-like growth factor receptor binding; Protein binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.