"CDK9" Related Products

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Recombinant Human Cyclin-Dependent Kinase 9, GST-tagged, Active

Cat. No. : CDK9-280H
Product Overview : Recombinant human full-length CDK9 and CyclinK were co-expressed by baculovirus inSf9insect cells using an N-terminal GST tag on both proteins. MW=68 kDa and CyclinK~67 kDa.
Description : CDK9/CyclinK is a member of the cyclin-dependent protein kinase (CDK) family. CDK9 is closely related to cdc28 and cdc2 and is an important regulator of the cell cycle. CDK9 is a component of the multiprotein complex TAK/P-TEFβ. CDK9 can modulate RNA polymerase II-directed transcription by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. CDK9 forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. CDK9 also interacts with the HIV-1 Tat protein which suggested a possible involvement of this protein in AIDS.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Purity : Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : CDK9 cyclin-dependent kinase 9 [ Homo sapiens ]
Synonyms : CDK9; cyclin-dependent kinase 9; TAK; C-2k; CTK1; CDC2L4; PITALRE; cyclin-dependent kinase 9 (CDC2-related kinase);Cell division protein kinase 9;EC2.7.11.22;EC2.7.11.23; Cyclin-dependent kinase 9; Serine/threonine-protein kinase; Cell division cycle 2-like protein kinase 4
Gene ID : 1025
mRNA Refseq : NM_001261
Protein Refseq : NP_001252
UniProt ID : P50750
Chromosome Location : 9q34.1
MIM : 603251
Pathway : Gene Expression; HIV Infection; Transcription
Function : ATP binding; DNA binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin-dependent protein kinase activity; nucleotide binding; protein binding; snRNA binding; transferase activity

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