"BLK" Related Products

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Recombinant Human B lymphoid Tyrosine Kinase, GST-tagged, Active

Cat. No.: BLK-250H
Product Overview: Recombinant full-length human BLK was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW = 84 kDa.
Description: BLK, also known as B lymphoid kinase, is a 55 kd tyrosine kinases with a SH3, SH2 and catalytic domains that contain consensus sequences of the src protein tyrosine kinase family. BLK is expressed specifically in the B cell lineage and plays a role in signal transduction pathway that is restricted to B lymphoid cells. Stimulation of resting B-lymphocytes with antibodies to surface immunoglobulin (sIgD or sIgM) induces activation of BLK.
Source: Sf9 insect cells using baculovirus.
Sequence: Full-length.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: BLK B lymphoid tyrosine kinase [ Homo sapiens ]
Synonyms: B lymphoid tyrosine kinase;MGC10442; BLK; BLK nonreceptor tyrosine kinase; EC 2.7.10.2; p55-BLK; B lymphocyte kinase
Gene ID: 640
mRNA Refseq: NM_001715
Protein Refseq: NP_001706
MIM: 191305
UniProt ID: P51451
Chromosome Location: 8p23-p22
Function: non-membrane spanning protein tyrosine kinase activity; ATP binding; nucleotide binding; protein binding; transferase activity

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