"CDC42BPA" Related Products

Recombinant Human CDC42BPA, GST-tagged, Active

Cat. No.: CDC42BPA-357H
Product Overview: Recombinant human MRCKalpha (1-473) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 73 kDa.
Description: Myotonic Dystrophy Kinase-Related Cdc42-Binding Kinase α (MRCKα) is a Cdc42/Rac/Rho interactive/binding serine/threonine kinase with multiple functional domains. MRCK are effectors of RhoA and Cdc42, respectively, for actin reorganization. MRCKα is a critical regulator of signal transduction pathways in eukaryotic cells that are known principally for their role in regulating the cytoskeleton, and they do so by recruiting a variety of downstream effector proteins.
Source: Sf9 insect cells using baculovirus.
Sequence: 1-473.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) [ Homo sapiens ]
Synonyms: CDC42BPA; CDC42 binding protein kinase alpha (DMPK-like); MRCK; MRCKA; PK428; FLJ23347; KIAA0451; DKFZp686L1738; DKFZp686P1738; CDC42-binding protein kinase alpha; ser-thr protein kinase PK428; CDC42 binidng protein kinase beta; CDC42-binding protein kinase alpha (DMPK-like); myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; ser-thr protein kinase related to the myotonic dystrophy protein kinase; EC; OTTHUMP00000035727; OTTHUMP00000035728; DMPK-like alpha
Gene ID: 8476
mRNA Refseq: NM_003607
Protein Refseq: NP_003598
MIM: 603412
UniProt ID: Q5VT25
Chromosome Location: 1q42.11
Function: ATP binding; identical protein binding; magnesium ion binding; nucleotide binding; protein serine/threonine kinase activity; small GTPase regulator activity; transferase activity; zinc ion binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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