Recombinant Human Myosin IIIB, GST-tagged, Active

• Cat.No.: MYO3B-367H
• Product Overview: Recombinant human MYO3beta (1-326) was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 63 kDa.

Specification

• Cat. No.: MYO3B-367H
• Description: MYO3β is a member of the Class III myosins that are actin-dependent motor proteins containing an amino-terminal kinase domain. MYO3β contains a N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3β gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis shows expression of a 7-kb MYO3β transcript in the human retina but not in a RPE cell line. The MYO3β gene transcript is also detected in the kidney, intestine and testis. The MYO3β gene maps to chromosome 2q31.1-q31.2 by genomic sequence alignment.
• Source: Sf9 insect cells using baculovirus.
• Sequence: 1-326.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: MYO3B myosin IIIB [ Homo sapiens ]
• Synonyms: MYO3B; myosin IIIB; EC 2.7.11.1; Myosin-IIIB
• Gene ID: 140469
• mRNA Refseq: NM_001083615
• Protein Refseq: NP_001077084
• MIM: 610040
• UniProt ID: Q8WXR4
• Chromosome Location: 2q31.1-q31.2
• Function: ATP binding; actin binding; motor activity; nucleotide binding; protein serine/threonine kinase activity; transferase activity