"PRKCD" Related Products

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Recombinant Human Protein Kinase C, Delta, GST-tagged, Active

Cat. No.: PRKCD-401H
Product Overview: Recombinant human full-length PKCdelta was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=104 kDa.
Description: Protein kinase C delta (PKCδ) is a member of the protein kinase C (PKC) family of serine-threonine kinases. It is a 79 kd protein kinase that shows strict dependence on the presence of phospholipids, but shows no activation by Ca2+. Phosphatidylinositol is the most potent activator of PKC delta. Northern blot analysis indicated that PKCdelta is widely distributed in almost all the tissues and is a major isoform of PKC expressed in hemopoietic cells. PKCdelta is involved in fundamental cellular functions regulated by diacylglycerols and mimicked by phorbol esters.
Source: Sf9 insect cells using baculovirus.
Sequence: Full-length.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: PRKCD protein kinase C, delta [ Homo sapiens ]
Synonyms: PRKCD; protein kinase C, delta; MAY1; PKCD; MGC49908; nPKC-delta; Protein kinase C delta type; EC 2.7.11.13; protein kinase C delta VIII
Gene ID: 5580
mRNA Refseq: NM_006254
Protein Refseq: NP_006245
UniProt ID: Q05655
Chromosome Location: 3p21.31
MIM: 176977
Pathway: Chemokine signaling pathway; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; GnRH signaling pathway; Neurotrophin signaling pathway; Tight junction; Type II diabetes mellitus; Vascular smooth muscle contraction; Apoptosis; Signalling by NGF
Function: ATP binding; calcium-independent protein kinase C activity; enzyme activator activity; enzyme binding; insulin receptor substrate binding; metal ion binding; nucleotide binding; protein C-terminus binding; transferase activity; zinc ion binding

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