"RIPK2" Related Products

Expand
Expand

Recombinant Human RIPK2, GST-tagged, Active

Cat. No.: RIPK2-418H
Product Overview: Recombinant human RIPK2 (1-299) was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=59kDa.
Description: RIPK2 (RIP2; RICK) is a death domain-containing protein kinase encoding a predicted 540-amino acid protein which contains an N-terminal serine/threonine kinase catalytic domain and a C-terminal caspase activation and recruitment domain. RIPK2 is thought to regulate apoptosis induced by the FAS receptor pathway. RIPK2 has been shown to specifically interact with the CARD of ICE/caspase-1 and this interaction correlates with the processing of pro-caspase-1 and the formation of the active caspase-1 p20.
Source: Sf9 insect cells using baculovirus.
Sequence: 1-299.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: RIPK2 receptor-interacting serine-threonine kinase 2 [ Homo sapiens ]
Synonyms: RIPK2; receptor-interacting serine-threonine kinase 2; CARD-carrying kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; growth-inhibiting gene 30; receptor interacting protein 2; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; CCK; RICK; RIP2; CARD3; GIG30; CARDIAK; EC 2.7.11.1
Gene ID: 8767
mRNA Refseq: NM_003821
Protein Refseq: NP_003812
MIM: 603455
UniProt ID: O43353
Chromosome Location: 8q21
Pathway: NOD-like receptor signaling pathway; Neurotrophin signaling pathway; Signaling in Immune system; Signalling by NGF
Function: ATP binding; CARD domain binding; LIM domain binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; signal transducer activity; transferase activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.