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Recombinant Human PTPN7,GST-tagged,Active

Cat.No. : PTPN7-466H
Product Overview : Recombinant human full length PTPN7 was expressed inE.colicells using a N-terminal GST tag. MW=67kDa.
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Cat. No. : PTPN7-466H
Description : PTPN7 gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and negatively regulates ERK2 and p38 MAP-kinases activity. The PTPN7 was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway.
Source : E.coli.
Sequence : Full length.
Applications : Phosphatase Assay, Western Blot.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : PTPN7 protein tyrosine phosphatase, non-receptor type 7 [ Homo sapiens ]
Synonyms : PTPN7; protein tyrosine phosphatase, non-receptor type 7; EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase LC-PTP; LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP; Tyrosine-protein phosphatase non-receptor type 7
Gene ID : 5778
mRNA Refseq : NM_002832
Protein Refseq : NP_002823
UniProt ID : P35236
Chromosome Location : 1q32.1
MIM : 176889
Pathway : MAPK signaling pathway
Function : hydrolase activity; protein binding; protein tyrosine phosphatase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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