"PTPN7" Related Products

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Recombinant Human PTPN7,GST-tagged,Active

Cat. No.: PTPN7-466H
Product Overview: Recombinant human full length PTPN7 was expressed inE.colicells using a N-terminal GST tag. MW=67kDa.
Description: PTPN7 gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and negatively regulates ERK2 and p38 MAP-kinases activity. The PTPN7 was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway.
Source: E.coli.
Sequence: Full length.
Applications: Phosphatase Assay, Western Blot.
Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: PTPN7 protein tyrosine phosphatase, non-receptor type 7 [ Homo sapiens ]
Synonyms: PTPN7; protein tyrosine phosphatase, non-receptor type 7; EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase LC-PTP; LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP; Tyrosine-protein phosphatase non-receptor type 7
Gene ID: 5778
mRNA Refseq: NM_002832
Protein Refseq: NP_002823
UniProt ID: P35236
Chromosome Location: 1q32.1
MIM: 176889
Pathway: MAPK signaling pathway
Function: hydrolase activity; protein binding; protein tyrosine phosphatase activity

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