"PTPRA" Related Products


Recombinant Human PTPRA, GST-tagged, Active

Cat. No. : PTPRA-467H
Product Overview : Recombinant human PTPRA (174-802) was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=96 kDa.
Description : PTPRA (also known as LRP) is a member of the protein tyrosine phosphatase family and contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. PTPRA dephosphorylates SRC family kinases, potassium channels and NMDA receptors and exists as three alternatively spliced variants which encode two distinct isoforms. Absence of PTPRA compromises correct positioning of pyramidal neurons during development of mouse hippocampus.
Source : Sf9 insect cells using baculovirus.
Sequence : 174-802.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
22q13.33 : 20p13
PDB rendering based on 1p15. :

Gene Name : PTPRA protein tyrosine phosphatase, receptor type, A [ Homo sapiens ]
Synonyms : PTPRA; protein tyrosine phosphatase, receptor type, A; Leukocyte common antigen-related peptide (protein tyrosine phosphate); OTTHUMP00000030064; PTPLCA-related phosphatase; PTPase-alpha; protein tyrosine phosphatase, receptor type, alpha polypeptide; tyrosine phosphatase alpha; LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha; EC
Gene ID : 5786
mRNA Refseq : NM_002836
Protein Refseq : NP_002827
MIM : 176884
UniProt ID : P18433
Pathway : Axon guidance
Function : hydrolase activity; transmembrane receptor protein tyrosine phosphatase activity

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