Recombinant Human PDE3A, GST-tagged, Active
Cat.No. : | PDE3A-473H |
Product Overview : | Recombinanthuman PDE3A (669-end) was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=84kDa. |
- Specification
- Gene Information
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Cat. No. : | PDE3A-473H |
Description : | PDE3A is a member of the phosphodiesterase family of proteins that play a critical role in regulating intracellular levels of cAMP and cGMP. PDE3A has high affinity for both cAMP and cGMP and shows competitive inhibition of the cAMP hydrolytic activity by cGMP. Deletion of the N-terminus of PDE3A enhances the hydrolysis of cGMP relative to cAMP suggesting that the role of divergent N-termini of various PDEs could be to exert substrate specificity. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | 669-end. |
Applications : | PDE Assay. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
22q13.33 : | 12p12 |
Gene Name : | PDE3A phosphodiesterase 3A, cGMP-inhibited [ Homo sapiens ] |
Synonyms : | PDE3A; phosphodiesterase 3A, calmodulin-dependent; cGMP-inhibited 3",5"-cyclic phosphodiesterase A; cyclic GMP inhibited phosphodiesterase A; phosphodiesterase 3A; CGI-PDE; EC 3.1.4.17 |
Gene ID : | 5139 |
mRNA Refseq : | NM_000921 |
Protein Refseq : | NP_000912 |
MIM : | 123805 |
UniProt ID : | Q14432 |
Pathway : | Progesterone-mediated oocyte maturation; Purine metabolism; Signaling by GPCR; Insulin signaling pathway |
Function : | 3",5"-cyclic-AMP phosphodiesterase activity; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; hydrolase activity |
Products Types
◆ Recombinant Protein | ||
PDE3A-3988R | Recombinant Rat PDE3A Protein, His (Fc)-Avi-tagged | +Inquiry |
PDE3A-01H | Recombinant Human PDE3A Protein, His/GST-tagged | +Inquiry |
Pde3a-301R | Recombinant Rat Pde3a Protein, His/GST-tagged | +Inquiry |
PDE3A-018H | Recombinant Human PDE3A Protein, His/GST-tagged | +Inquiry |
PDE3A-4328R | Recombinant Rat PDE3A Protein | +Inquiry |
◆ Lysates | ||
PDE3A-001HCL | Recombinant Human PDE3A cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1835 | PDE3A TR-FRET Assay Kit | +Inquiry |
Kit-1834 | PDE3A Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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