"ACADVL" Related Products


Recombinant Human ACADVL, His-tagged

Cat.No. : ACADVL-26050TH
Product Overview : Recombinant full length Human ACADVL with an N terminal His tag; 636 amino acids including tag, MWt 68.5kDa.
Description : The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Protein length : 615 amino acids
Conjugation : HIS
Molecular Weight : 68.500kDa inclusive of tags
Source : E. coli
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM EDTA, 1mM DTT, pH 8.0
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Belongs to the acyl-CoA dehydrogenase family.
Gene Name : ACADVL acyl-CoA dehydrogenase, very long chain [ Homo sapiens ]
Official Symbol : ACADVL
Synonyms : ACADVL; acyl-CoA dehydrogenase, very long chain; acyl Coenzyme A dehydrogenase, very long chain; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD6; LCACD; VLCAD;
Gene ID : 37
mRNA Refseq : NM_000018
Protein Refseq : NP_000009
MIM : 609575
Uniprot ID : P49748
Chromosome Location : 17p13.1
Pathway : Activation of Chaperones by IRE1alpha, organism-specific biosystem; Beta oxidation of palmitoyl-CoA to myristoyl-CoA, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem;
Function : acyl-CoA dehydrogenase activity; fatty-acyl-CoA binding; flavin adenine dinucleotide binding; long-chain-acyl-CoA dehydrogenase activity; very long-chain-acyl-CoA dehydrogenase activity;

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