Recombinant Human ACADVL, His-tagged
Cat.No. : | ACADVL-26050TH |
Product Overview : | Recombinant full length Human ACADVL with an N terminal His tag; 636 amino acids including tag, MWt 68.5kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Protein length : | 615 amino acids |
Conjugation : | HIS |
Molecular Weight : | 68.500kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM EDTA, 1mM DTT, pH 8.0 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMAGGA AQLALDKSDSHPSDALTRKKPAKAE SKSFAVGMFKGQLTTDQVFPYPSVL NEEQTQFLKELVEPVSRFFEEVNDP AKNDALEMVEETTWQGLKELGAFGL QVPSELGGVGLCNTQYARLVEIVGM HDLGVGITLGAHQSIGFKGILLFGT KAQKEKYLPKLASGETVAAFCLTEP SSGSDAASIRTSAVPSPCGKYYTLN GSKLWISNGGLADIFTVFAKTPVTD PATGAVKEKITAFVVERGFGGITHG PPEKKMGIKASNTAEVFFDGVRVPS ENVLGEVGSGFKVAMHILNNGRFGM AAALAGTMRGIIAKAVDHATNRTQF GEKIHNFGLIQEKLARMVMLQYVTE SMAYMVSANMDQGATDFQIEAAISK IFGSEAAWKVTDECIQIMGGMGFMK EPGVERVLRDLRIFRIFEGTNDILR LFVALQGCMDKGKELSGLGSALKNP FGNAGLLLGEAGKQLRRRAGLGSGL SLSGLVHPELSRSGELAVRALEQFA TVVEAKLIKHKKGIVNEQFLLQRLA DGAIDLYAMVVVLSRASRSLSEGHP TAQHEKMLCDTWCIEAAARIREGMA ALQSDPWQQELYRNFKSISKALVER GGVVTSNPLGF |
Sequence Similarities : | Belongs to the acyl-CoA dehydrogenase family. |
Gene Name : | ACADVL acyl-CoA dehydrogenase, very long chain [ Homo sapiens ] |
Official Symbol : | ACADVL |
Synonyms : | ACADVL; acyl-CoA dehydrogenase, very long chain; acyl Coenzyme A dehydrogenase, very long chain; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD6; LCACD; VLCAD; |
Gene ID : | 37 |
mRNA Refseq : | NM_000018 |
Protein Refseq : | NP_000009 |
MIM : | 609575 |
Uniprot ID : | P49748 |
Chromosome Location : | 17p13.1 |
Pathway : | Activation of Chaperones by IRE1alpha, organism-specific biosystem; Beta oxidation of palmitoyl-CoA to myristoyl-CoA, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem; |
Function : | acyl-CoA dehydrogenase activity; fatty-acyl-CoA binding; flavin adenine dinucleotide binding; long-chain-acyl-CoA dehydrogenase activity; very long-chain-acyl-CoA dehydrogenase activity; |
Products Types
◆ Recombinant Protein | ||
ACADVL-27H | Recombinant Human ACADVL Protein, His-tagged | +Inquiry |
Acadvl-28M | Recombinant Mouse Acadvl Protein, His-tagged | +Inquiry |
Acadvl-504M | Recombinant Mouse Acadvl Protein, MYC/DDK-tagged | +Inquiry |
ACADVL-95R | Recombinant Rat ACADVL Protein, His (Fc)-Avi-tagged | +Inquiry |
ACADVL-440R | Recombinant Rat ACADVL Protein | +Inquiry |
◆ Lysates | ||
ACADVL-9111HCL | Recombinant Human ACADVL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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