"AFF2" Related Products

Recombinant Human AFF2

Cat.No. : AFF2-26444TH
Product Overview : Recombinant fragment of Human AFF2 with N terminal proprietary tag. Predicted MW 37.84 kDa.
Description : This gene encodes a putative transcriptional activator that is a member of the AF4\FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.
Protein length : 111 amino acids
Molecular Weight : 37.840kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Brain (most abundant in hippocampus and amygdala), placenta and lung.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : KNEPSFFPEQKNRIIPPHQDNTHPSAPMPPPSVVILNSTL IHSNRKSKPEWSRDSHNPSTVLASQASGQPNKMQTLTQDQ SQAKLEDFFVYPAEQPQIGEVEESNPSAKED
Sequence Similarities : Belongs to the AF4 family.
Gene Name : AFF2 AF4/FMR2 family, member 2 [ Homo sapiens ]
Official Symbol : AFF2
Synonyms : AFF2; AF4/FMR2 family, member 2; FMR2, fragile X mental retardation 2; AF4/FMR2 family member 2; FRAXE;
Gene ID : 2334
mRNA Refseq : NM_001169122
Protein Refseq : NP_001162593
MIM : 300806
Uniprot ID : P51816
Chromosome Location : Xq28
Function : G-quadruplex RNA binding;

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