Recombinant Human AKR7A3, His-tagged

• Cat.No.: AKR7A3-26727TH
• Product Overview: Recombinant full length Human AKR7A3 with a N terminal His tag. 370 amino acids with a predicted MWt 41.6 kDa including tag.

Specification

• Description: Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.
• Protein length: 331 amino acids
• Conjugation: HIS
• Molecular Weight: 41.600kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
• Biological activity: Specific activity: approximately
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 0.58% Sodium chloride, 10% Glycerol
• Storage: Please see Notes section
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELEM SRQLSRARPA TVLGAMEMGR RMDAPTSAAV TRAFLERGHT EIDTAFVYSE GQSETILGGL GLRLGGSDCR VKIDTKAIPL FGNSLKPDSL RFQLETSLKR LQCPRVDLFY LHMPDHSTPV EETLRACHQL HQEGKFVELG LSNYAAWEVA EICTLCKSNG WILPTVYQGM YNAITRQVET ELFPCLRHFG LRFYAFNPLA GGLLTGKYKY EDKDGKQPVG RFFGNTWAEM YRNRYWKEHH FEGIALVEKA LQAAYGASAP SMTSATLRWM YHHSQLQGAH GDAVILGMSS LEQLEQNLAA AEEGPLEPAV VDAFNQAWHL VAHECPNYFR
• Sequence Similarities: Belongs to the aldo/keto reductase 2 family.

Gene Information

• Gene Name: AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) [ Homo sapiens ]
• Official Symbol: AKR7A3
• Synonyms: AKR7A3; aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase); aflatoxin B1 aldehyde reductase member 3
• Gene ID: 22977
• mRNA Refseq: NM_012067
• Protein Refseq: NP_036199
• MIM: 608477
• Uniprot ID: O95154
• Chromosome Location: 1p36.13
• Pathway: Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, conserved biosystem
• Function: aldo-keto reductase (NADP) activity; electron carrier activity; oxidoreductase activity