Recombinant Human ANXA6, His-tagged

• Cat.No.: ANXA6-27320TH
• Product Overview: Recombinant full length protein, corresponding to amino acids 1-673 of Human Annexin VI with His tag. MWt 79 kDa

Specification

• Description: Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Purity: Immunogen affinity purified
• Storage buffer: Preservative: 100mM ImidazoleConstituents: 0.5M Sodium chloride, 20mM Tris HCl, 1mM Beta mercaptoethanol, pH 8
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the annexin family.Contains 8 annexin repeats.

Gene Information

• Gene Name: ANXA6 annexin A6 [ Homo sapiens ]
• Official Symbol: ANXA6
• Synonyms: ANXA6; annexin A6; ANX6
• Gene ID: 309
• mRNA Refseq: NM_001155
• Protein Refseq: NP_001146
• MIM: 114070
• Uniprot ID: P08133
• Chromosome Location: 5q33.1
• Pathway: Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Prostaglandin Synthesis and Regulation, organism-specific biosystem
• Function: calcium ion binding; calcium-dependent phospholipid binding; protein binding