Native Human APOC3

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Native Human APOC3

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Cat.No. : APOC3-27333TH
Product Overview : Full length native Apolipoprotein CIII purified from human plasma, VLDL.
Description : Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein.APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles.The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes.The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed.An increase in ap°C-III levels induces the development of hypertriglyceridemia.
Form : Lyophilised:Reconstitute with 59.9ul distilled water.
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10mM Ammonium bicarbonate, pH 7.4
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Gene Name : APOC3 apolipoprotein C-III [ Homo sapiens ]
Official Symbol : APOC3
Synonyms : APOC3; apolipoprotein C-III;
Gene ID : 345
mRNA Refseq : NM_000040
Protein Refseq : NP_000031
MIM : 107720
Uniprot ID : P02656
Chromosome Location : 11q23-qter
Pathway : Chylomicron-mediated lipid transport, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
Function : cholesterol binding; enzyme regulator activity; high-density lipoprotein particle receptor binding; lipase inhibitor activity; phospholipid binding;

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