"ARHGDIB" Related Products

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Recombinant Human ARHGDIB, GST-tagged

Cat.No.: ARHGDIB-27088TH
Product Overview: Recombinant full length D4 GDI protein (Human) tagged to GST
Description: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al.
Conjugation: GST
Source: E. coli
Form: Liquid
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids: Protein contains a GST tag.
Sequence Similarities: Belongs to the Rho GDI family.
Gene Name: ARHGDIB Rho GDP dissociation inhibitor (GDI) beta [ Homo sapiens ]
Official Symbol: ARHGDIB
Synonyms: ARHGDIB; Rho GDP dissociation inhibitor (GDI) beta; GDIA2, GDID4, RAP1GN1; rho GDP-dissociation inhibitor 2; Ly GDI; RhoGDI2;
Gene ID: 397
mRNA Refseq: NM_001175
Protein Refseq: NP_001166
MIM: 602843
Uniprot ID: P52566
Chromosome Location: 12p12.3
Pathway: Caspase cascade in apoptosis, organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; G13 Signaling Pathway, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, conserved biosystem;
Function: GTPase activator activity; Rho GDP-dissociation inhibitor activity;

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