Recombinant Human BID
Cat.No. : | BID-26711TH |
Product Overview : | Recombinant full length human Bid with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system; amino acids 1-95, 52kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. |
Tissue specificity : | Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is |
Form : | Liquid |
Storage buffer : | Preservative: 150mM ImidazoleConstituents: 25% Glycerol, 50mM MOPS, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Gene Name : | BID BH3 interacting domain death agonist [ Homo sapiens ] |
Official Symbol : | BID |
Synonyms : | BID; BH3 interacting domain death agonist; BH3-interacting domain death agonist; |
Gene ID : | 637 |
mRNA Refseq : | NM_001196 |
Protein Refseq : | NP_001187 |
MIM : | 601997 |
Uniprot ID : | P55957 |
Chromosome Location : | 22q11.2 |
Pathway : | Activation and oligomerization of BAK protein, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Activation, myristolyation of BID and translocation to mitochondria, organism-specific biosystem; Activation, translocation and oligomerization of BAX, organism-specific biosystem; |
Function : | death receptor binding; protein binding; ubiquitin protein ligase binding; |
Products Types
◆ Recombinant Protein | ||
BID-2006H | Recombinant Human BID Protein, His-tagged | +Inquiry |
Bid-711M | Recombinant Mouse Bid Protein, MYC/DDK-tagged | +Inquiry |
BID-1032M | Recombinant Mouse BID Protein, His (Fc)-Avi-tagged | +Inquiry |
Bid-4029M | Active Recombinant Mouse Bid protein(Met1-Asp195), His&GST-tagged | +Inquiry |
BID-2592H | Recombinant Human BID protein, His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
BID-8456HCL | Recombinant Human BID 293 Cell Lysate | +Inquiry |
BID-8455HCL | Recombinant Human BID 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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