Native Human C1QA

• Cat.No.: C1QA-26126TH
• Product Overview: Full length native Human C1q from pooled normal Human serum, MWt 410kDa.

Specification

• Description: This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q.
• Source: human serum
• Form: Lyophilised:Use of water to a volume equivalent to the original fill volume is recommended. Slight turbidity may result on reconstitution.
• Molecular Mass: 410kDa
• Purity: by SDS-PAGE
• Storage: Store at +4°C .
• Storage Buffer: pH: 7.50Constituents:1.74% Sodium chloride, 0.29% Sodium EDTA

Gene Information

• Gene Name: C1QA complement component 1, q subcomponent, A chain [ Homo sapiens ]
• Official Symbol: C1QA
• Synonyms: C1QA; complement component 1, q subcomponent, A chain; complement component 1, q subcomponent, alpha polypeptide; complement C1q subcomponent subunit A; complement component C1q, A chain
• Gene ID: 712
• mRNA Refseq: NM_015991
• Protein Refseq: NP_057075
• MIM: 120550
• UniProt ID: P02745
• Chromosome Location: 1p36.3-p34.1
• Pathway: Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Classical antibody-mediated complement activation, organism-specific biosystem; Complement Activation, Classical Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem