Recombinant Human CACNB2 CACNB2-26766TH

Recombinant Human CACNB2

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Recombinant Human CACNB2

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Cat.No. : CACNB2-26766TH
Product Overview : Recombinant fragment of Human CACNB2 with N terminal proprietary tag, 35.42kDa inclusive of tag.
Description : This gene encodes a subunit of a voltage-dependent calcium channel protein which is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome which is an autoimmune disorder. Mutations in this gene are associated with Brugada symdrome. Alternatively spliced variants have been identified for this gene.
Protein length : 89 amino acids
Molecular Weight : 35.420kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Expressed in all tissues.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : PSSRKSTPPSSAIDI DATGLDAEENDIPAN HRSPKPSANSVTSPH SKEKRMPFFKKTEHT PPYDVVPSMRPVVLV GPSLKGYEVTDMMQ
Sequence Similarities : Belongs to the calcium channel beta subunit family.Contains 1 SH3 domain.
Gene Name : CACNB2 calcium channel, voltage-dependent, beta 2 subunit [ Homo sapiens ]
Official Symbol : CACNB2
Synonyms : CACNB2; calcium channel, voltage-dependent, beta 2 subunit; CACNLB2, MYSB; voltage-dependent L-type calcium channel subunit beta-2;
Gene ID : 783
mRNA Refseq : NM_000724
Protein Refseq : NP_000715
MIM : 600003
Uniprot ID : Q08289
Chromosome Location : 10p12
Pathway : Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem;
Function : calcium channel activity; calcium channel regulator activity; protein binding; voltage-gated calcium channel activity; voltage-gated ion channel activity;

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