Recombinant Human Myelin Basic Protein, GST-tagged

• Cat.No.: MBP-1469H
• Product Overview: Recombinant full length human MBP was expressed inE. colicells using a N-terminal GST tag. MW = 36kDa.

Specification

• Cat. No.: MBP-1469H
• Description: MBP or Myelin Basic Protein forms dimers across the cytoplasmic apposition during the formation of myelin. The region of the protein involved in folding, polymerization and substrate specificities is conserved in various species and it may have a specialized role in protein-lipid interactions in the myelin membrane. MBP is an efficient substrate for numerous protein kinases and share similarities with the MARCKS protein in terms of having extended conformations regulated by their environment, N-terminal modifications, a dual nature of interactions with lipids, and binding to actin and Ca2+-calmodulin.
• Source: E. coli.
• Sequence: Full length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Publication:
  TRC40 can deliver short secretory proteins to the Sec61 translocon (2012)

Gene Information

• Gene Name: MBP myelin basic protein [ Homo sapiens ]
• Synonyms: MBP; myelin basic protein; MGC99675; Myelin A1 protein; Myelin membrane encephalitogenic protein; Golli-mbp; MGC99675; OTTHUMP00000174383; OTTHUMP00000174384; OTTHUMP00000174385; OTTHUMP00000174386; Myelin A1 protein; Myelin membrane encephalitogenic protein; myelin basic protein
• Gene ID: 4155
• mRNA Refseq: NM_001025081
• Protein Refseq: NP_001020252
• MIM: 159430
• UniProt ID: P02686
• Chromosome Location: 18q23
• Function: structural constituent of myelin sheath