Recombinant Human CAMKK1

• Cat.No.: CAMKK1-26209TH
• Product Overview: Recombinant full length (human) protein with an N terminal enzyme tag. Expressed by baculovirus in Sf9 insect cells.

Specification

• Description: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.
• Biological activity: Specific Activity: 10 nmol/min/mg
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Contains 1 protein kinase domain.

Gene Information

• Gene Name: CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha [ Homo sapiens ]
• Official Symbol: CAMKK1
• Synonyms: CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; calcium/calmodulin-dependent protein kinase kinase 1; CAMKKA; DKFZp761M0423; MGC34095
• Gene ID: 84254
• mRNA Refseq: NM_032294
• Protein Refseq: NP_115670
• MIM: 611411
• Uniprot ID: Q8N5S9
• Chromosome Location: 17p13.3
• Pathway: Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; CREB phosphorylation through the activation of CaMKK, organism-specific biosystem; Neuronal System, organism-specific biosystem
• Function: ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding