Recombinant Human CANX
Cat.No. : | CANX-27552TH |
Product Overview : | Recombinant fragment of Human Calnexin - ER membrane marker, lumenal domain ; 462aa, 52.5kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. |
Protein length : | 461 amino acids |
Molecular Weight : | 52.500kDa |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:0.02% DTT, 20% Glycerol, 0.32% Tris HCl |
Storage : | Please see Notes section |
Sequences of amino acids : | MHDGHDDDVI DIEDDLDDVI EEVEDSKPDT TAPPSSPKVT YKAPVPTGEV YFADSFDRGT LSGWILSKAK KDDTDDEIAK YDGKWEVEEM KESKLPGDKG LVLMSRAKHH AISAKLNKPF LFDTKPLIVQ YEVNFQNGIE CGGAYVKLLS KTPELNLDQF HDKTPYTIMF GPDKCGEDYK LHFIFRHKNP KTGIYEEKHA KRPDADLKTY FTDKKTHLYT LILNPDNSFE ILVDQSVVNS GNLLNDMTPP VNPSREIEDP EDRKPEDWDE RPKIPDPEAV KPDDWDEDAP AKIPDEEATK PEGWLDDEPE YVPDPDAEKP EDWDEDMDGE WEAPQIANPR CESAPGCGVW QRPVIDNPNY KGKWKPPMID NPSYQGIWKP RKIPNPDFFE DLEPFRMTPF SAIGLELWSM TSDIFFDNFI ICADRRIVDD WANDGWGLKK AADGAAEPGV VGQMIEAAEE RP |
Sequence Similarities : | Belongs to the calreticulin family. |
Gene Name : | CANX calnexin [ Homo sapiens ] |
Official Symbol : | CANX |
Synonyms : | CANX; calnexin; CNX; IP90; major histocompatibility complex class I antigen binding protein p88; P90; |
Gene ID : | 821 |
mRNA Refseq : | NM_001024649 |
Protein Refseq : | NP_001019820 |
MIM : | 114217 |
Uniprot ID : | P27824 |
Chromosome Location : | 5q35 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; |
Function : | calcium ion binding; protein binding; sugar binding; unfolded protein binding; |
Products Types
◆ Recombinant Protein | ||
CANX-2707H | Recombinant Human CANX protein(31-470 aa), C-His-tagged | +Inquiry |
CANX-8631H | Recombinant Human CANX protein(Met1-Pro481), hFc-tagged | +Inquiry |
CANX-1210M | Recombinant Mouse CANX Protein, His (Fc)-Avi-tagged | +Inquiry |
CANX-0350H | Recombinant Human CANX Protein, GST-Tagged | +Inquiry |
Canx-305M | Recombinant Mouse Calnexin Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CANX-1347HCL | Recombinant Human CANX cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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