Human CANX Knockdown Cell Lysate

• Cat.No.: CANX-081HKCL
• Product Overview: WB-validated CANX Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 68 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg CANX KD HeLa cell lysate
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Antigen processing and presentation
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: CANX calnexin [ Homo sapiens (human) ]
• Official Symbol: CANX
• Synonyms: CANX; calnexin; CNX; IP90; major histocompatibility complex class I antigen binding protein p88; P90; major histocompatibility complex class I antigen-binding protein p88; FLJ26570
• Gene ID: 821
• mRNA Refseq: NM_001024649
• Protein Refseq: NP_001019820
• MIM: 114217
• UniProt ID: P27824