| Description : |
Calnexin is a calcium-binding protein that belongs to the calreticulin family. It interacts with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Ass centigradeiated with partial T-cell antigen receptor complexes that escape the ER of immature thym centigradeytes, it may function as a signaling complex regulating thym centigradeyte maturation. Additionally it may play a role in receptor-mediated end centigradeytosis at the synapse. |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
His |
| Predicted N Terminal : |
His 21 |
| Form : |
Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
| Molecular Mass : |
The recombinant mouse Canx consists of 473 amino acids and predicts a molecular mass of 53.9 kDa. |
| Protein length : |
Met1-Pro482 |
| Endotoxin : |
< 1.0 EU per μg protein as determined by the LAL method. |
| Purity : |
> 90 % as determined by SDS-PAGE. |
| Storage : |
Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
