Recombinant Human CAST
Cat.No. : | CAST-27210TH |
Product Overview : | Recombinant fragment corresponding to amino acids 582-669 of Human Calpastatin with an N terminal proprietary tag; Predicted MWt 35.31 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. |
Protein length : | 88 amino acids |
Molecular Weight : | 35.310kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | QPDPDENKPMEDKVKEKAKAEHRDK LGERDDTIPPEYRHLLDDNGQDKPV KPPTKKSEDSKKPADDQDPIDALSG DLDSCPSTTETSQ |
Sequence Similarities : | Belongs to the protease inhibitor I27 (calpastatin) family. |
Gene Name : | CAST calpastatin [ Homo sapiens ] |
Official Symbol : | CAST |
Synonyms : | CAST; calpastatin; |
Gene ID : | 831 |
mRNA Refseq : | NM_001042440 |
Protein Refseq : | NP_001035905 |
MIM : | 114090 |
Uniprot ID : | P20810 |
Chromosome Location : | 5q14-q22 |
Function : | calcium-dependent cysteine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
CAST-0441H | Recombinant Human CAST Protein, GST-Tagged | +Inquiry |
CAST-628H | Recombinant Human CAST Protein, His&GST-tagged | +Inquiry |
Cast-776M | Recombinant Mouse Cast Protein, MYC/DDK-tagged | +Inquiry |
CAST-1350H | Recombinant Human CAST Protein (1-667 aa), His-tagged | +Inquiry |
CAST-807R | Recombinant Rat CAST Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CAST-7824HCL | Recombinant Human CAST 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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