Recombinant Human CAST, GST-tagged
Cat.No. : | CAST-10743H |
Product Overview : | Recombinant Human CAST protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | N-term-350a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | CAST calpastatin [ Homo sapiens ] |
Official Symbol : | CAST |
Synonyms : | CAST; calpastatin; calpain inhibitor; sperm BS-17 component; BS-17; MGC9402; |
Gene ID : | 831 |
mRNA Refseq : | NM_001042440 |
Protein Refseq : | NP_001035905 |
MIM : | 114090 |
UniProt ID : | P20810 |
Chromosome Location : | 5q14-q22 |
Function : | calcium-dependent cysteine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
CAST-1350H | Recombinant Human CAST Protein (1-667 aa), His-tagged | +Inquiry |
Cast-776M | Recombinant Mouse Cast Protein, MYC/DDK-tagged | +Inquiry |
CAST-0441H | Recombinant Human CAST Protein, GST-Tagged | +Inquiry |
CAST-807R | Recombinant Rat CAST Protein, His (Fc)-Avi-tagged | +Inquiry |
CAST-628H | Recombinant Human CAST Protein, His&GST-tagged | +Inquiry |
◆ Lysates | ||
CAST-7824HCL | Recombinant Human CAST 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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