||Recombinant fragment, corresponding to amino acids 163-541 of Human TCP1 epsilon with an N terminal His tag. Predicted MWt: 43 kDa.
||The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. In addition, three pseudogenes of this gene have been identified.
||Lyophilised:Reconstitute with 65 μl aqua dest.
||Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
||Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequences of amino acids:
||EPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERR DVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMP KKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQ KYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQ NNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFA GLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMI IEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALA VSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNP IQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIE TLIGKKQQISLATQMVRMILKIDDIRKPGESEE