Recombinant Human CD274
| Cat.No. : | CD274-27112TH |
| Product Overview : | Recombinant fragment corresponding to aa 141-240 of human CD274 with a proprietary tag; 36.63kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
| Description : | Programmed cell death 1 ligand 1 (PD-L1) also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene. |
| Protein length : | 100 amino acids |
| Molecular Weight : | 36.630kDa inclusive of tags |
| Source : | Wheat germ |
| Tissue specificity : | Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. |
| Biological activity : | This product is useful for Antibody Production and Protein Array |
| Form : | Liquid |
| Purity : | Proprietary Purification |
| Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced. |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | ILVVDPVTSEHELTCQAEGYPKAEV IWTSSDHQVLSGKTTTTNSKREEKL FNVTSTLRINTTTNEIFYCTFRRLD PEENHTAELVIPELPLAHPPNERTH |
| Sequence Similarities : | Belongs to the immunoglobulin superfamily. BTN/MOG family.Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| Gene Name : | CD274 CD274 molecule [ Homo sapiens ] |
| Official Symbol : | CD274 |
| Synonyms : | CD274; CD274 molecule; CD274 antigen , PDCD1LG1, programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; B7 H; B7 H1; B7H1; PD L1; PDL1; |
| Gene ID : | 29126 |
| mRNA Refseq : | NM_014143 |
| Protein Refseq : | NP_054862 |
| MIM : | 605402 |
| Uniprot ID : | Q9NZQ7 |
| Chromosome Location : | 9p24.1 |
| Pathway : | Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; |
| Function : | protein binding; protein tyrosine phosphatase activity; receptor activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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