Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

Recombinant Human CD8B

Cat.No. : CD8B-27892TH
Product Overview : Recombinant full length Human CD8 beta with a proprietary tag; Predicted MW 52.8 kDa inclusive of tag.
  • Specification
  • Gene Information
  • Related Products
Description : The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Protein length : 243 amino acids
Molecular Weight : 52.800kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Isoform 1, isoform 3, isoform 5, isoform 6, isoform 7 and isoform 8 are expressed in both thymus and peripheral CD8+ T-cells. Expression of isoform 1 is higher in thymus CD8+ T-cells than in peripheral CD8+ T-cells. Expression of isoform 6 is higher in pe
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.31% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MRPRLWLLLAAQLTVLHGNSVLQQT PAYIKVQTNKMVMLSCEAKISLSNM RIYWLRQRQAPSSDSHHEFLALWDS AKGTIHGEEVEQEKIAVFRDASRFI LNLTSVKPEDSGIYFCMIVGSPELT FGKGTQLSVVDFLPTTAQPTKKSTL KKRVCRLPRPETQKGPLCSPITLGL LVAGVLVLLVSLGVAIHLCCRRRRA RLRFMKQPQGEGISGTFVPQCLHGY YSNTTTSQKLLNPWILKT
Sequence Similarities : Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Gene Name : CD8B CD8b molecule [ Homo sapiens ]
Official Symbol : CD8B
Synonyms : CD8B; CD8b molecule; CD8 antigen, beta polypeptide 1 (p37) , CD8B1; T-cell surface glycoprotein CD8 beta chain;
Gene ID : 926
mRNA Refseq : NM_001178100
Protein Refseq : NP_001171571
MIM : 186730
Uniprot ID : P10966
Chromosome Location : 2p12
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem;
Function : MHC class I protein binding; coreceptor activity; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All CD8B Products

Required fields are marked with *

My Review for All CD8B Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends