Recombinant Human CD97
Cat.No. : | CD97-26331TH |
Product Overview : | Recombinant fragment of Human CD97 (aa 421-529) with a N terminal proprietary tag: predicted molecular weight 37.62 kDa, inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. |
Protein length : | 109 amino acids |
Molecular Weight : | 37.620kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and p |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNS PILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKS DSDRGGHWATEGCQVLGSKNGSTTCQCSH |
Sequence Similarities : | Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.Contains 5 EGF-like domains.Contains 1 GPS domain. |
Gene Name : | CD97 CD97 molecule [ Homo sapiens ] |
Official Symbol : | CD97 |
Synonyms : | CD97; CD97 molecule; CD97 antigen; leukocyte antigen CD97; seven transmembrane helix receptor; seven span transmembrane protein; seven transmembrane; heterodimeric receptor associated with inflammation; TM7LN1; |
Gene ID : | 976 |
mRNA Refseq : | NM_001025160 |
Protein Refseq : | NP_001020331 |
MIM : | 601211 |
Uniprot ID : | P48960 |
Chromosome Location : | 19p13 |
Pathway : | Class B/2 (Secretin family receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem; |
Function : | G-protein coupled receptor activity; calcium ion binding; receptor activity; signal transducer activity; transmembrane signaling receptor activity; |
Products Types
◆ Recombinant Protein | ||
CD97-708H | Recombinant Human CD97 Protein, His-tagged | +Inquiry |
CD97-4378H | Recombinant Human CD97 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD97-0889H | Recombinant Human CD97 Protein, GST-Tagged | +Inquiry |
CD97-3134H | Active Recombinant Human CD97, Fc tagged | +Inquiry |
CD97-2229H | Active Recombinant Human CD97 protein, His-tagged | +Inquiry |
◆ Lysates | ||
CD97-2207HCL | Recombinant Human CD97 cell lysate | +Inquiry |
CD97-2475HCL | Recombinant Human CD97 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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