Recombinant Human TRAF2 Protein, GST-tagged
Cat.No. : | TRAF2-1500H |
Product Overview : | Recombinant full-length human TRAF2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | TRAF2 (also known as TNF receptor-associated factor 2) belongs to the TNF receptor associated factor (TRAF) protein family that mediates signal transduction from members of the TNF receptor superfamily. TRAF2 is involved in TNF-alpha-mediated activation of MAPK8/JNK and NF-κB pathway. TRAF2 interacts with TNF receptors and forms a heterodimeric complex with TRAF1. The TRAF1-TRAF2 complex interacts with IAPs to mediate the anti-apoptotic signals from TNF receptors. TRAF2 also interacts with TRADD, a TNF receptor associated apoptotic signal transducer, to ensure the recruitment of IAPs for the direct inhibition of caspase activation |
Source : | Insect cell |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Molecular Mass : | 89 kDa |
Purity : | >70% |
Storage : | Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Storage Buffer : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Gene Name : | TRAF2 TNF receptor-associated factor 2 [ Homo sapiens ] |
Official Symbol : | TRAF2 |
Synonyms : | TRAF2; TNF receptor-associated factor 2; TRAP3; E3 ubiquitin-protein ligase TRAF2; tumor necrosis factor type 2 receptor associated protein 3; tumor necrosis factor type 2 receptor-associated protein 3; TRAP; MGC:45012; |
Gene ID : | 7186 |
mRNA Refseq : | NM_021138 |
Protein Refseq : | NP_066961 |
MIM : | 601895 |
UniProt ID : | Q12933 |
Products Types
◆ Recombinant Protein | ||
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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