Recombinant Human TRAF2 Protein, GST-tagged


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Recombinant Human TRAF2 Protein, GST-tagged

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Cat.No. : TRAF2-1500H
Product Overview : Recombinant full-length human TRAF2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : TRAF2 (also known as TNF receptor-associated factor 2) belongs to the TNF receptor associated factor (TRAF) protein family that mediates signal transduction from members of the TNF receptor superfamily. TRAF2 is involved in TNF-alpha-mediated activation of MAPK8/JNK and NF-κB pathway. TRAF2 interacts with TNF receptors and forms a heterodimeric complex with TRAF1. The TRAF1-TRAF2 complex interacts with IAPs to mediate the anti-apoptotic signals from TNF receptors. TRAF2 also interacts with TRADD, a TNF receptor associated apoptotic signal transducer, to ensure the recruitment of IAPs for the direct inhibition of caspase activation
Source : Insect cell
Species : Human
Tag : GST
Form : Liquid
Molecular Mass : 89 kDa
Purity : >70%
Storage : Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Storage Buffer : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Gene Name : TRAF2 TNF receptor-associated factor 2 [ Homo sapiens ]
Official Symbol : TRAF2
Synonyms : TRAF2; TNF receptor-associated factor 2; TRAP3; E3 ubiquitin-protein ligase TRAF2; tumor necrosis factor type 2 receptor associated protein 3; tumor necrosis factor type 2 receptor-associated protein 3; TRAP; MGC:45012;
Gene ID : 7186
mRNA Refseq : NM_021138
Protein Refseq : NP_066961
MIM : 601895
UniProt ID : Q12933

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