Recombinant Human CDKN3

• Cat.No.: CDKN3-26472TH
• Product Overview: Recombinant full-length human CDKN3 was expressed by baculovirus in Sf9 insect cells using an N-terminal tag, 51kDa.

Specification

• Description: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Sodium chloride, 50mM Tris HCl, 0.25mM DTT, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein-tyrosine phosphatase family.

Gene Information

• Gene Name: CDKN3 cyclin-dependent kinase inhibitor 3 [ Homo sapiens ]
• Official Symbol: CDKN3
• Synonyms: CDKN3; cyclin-dependent kinase inhibitor 3; CDI1; CDK2 associated dual specificity phosphatase; cyclin dependent kinase inhibitor; KAP; kinase associated phosphatase
• Gene ID: 1033
• mRNA Refseq: NM_001130851
• Protein Refseq: NP_001124323
• MIM: 123832
• Uniprot ID: Q16667
• Chromosome Location: 14q22
• Function: hydrolase activity; protein binding; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity