- Chicken(1)
- Human(6)
- Mouse(2)
- Rhesus Macaque(1)
- Zebrafish(1)
Recombinant Human CFL2, His-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
| Cat.No. : | CFL2-26843TH |
| Product Overview : | Recombinant full length Human Cofilin 2 with an N terminal His tag; 186aa, 20.9kDa inclusive of tag. |
| Description : | This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. |
| Protein length : | 166 amino acids |
| Conjugation : | HIS |
| Molecular Weight : | 20.900kDa inclusive of tags |
| Source : | E. coli |
| Tissue specificity : | Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues. |
| Form : | Liquid |
| Purity : | >90% by SDS-PAGE |
| Storage buffer : | pH: 8.00Constituents:0.32% Tris HCl, 10% Glycerol, 0.04% DTT, 0.29% Sodium chloride |
| Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Sequences of amino acids : | MGSSHHHHHHSSGLV PRGSHMASGVTVNDE VIKVFNDMKVRKSST QEEIKKRKKAVLFCL SDDKRQIIVEEAKQI LVGDIGDTVEDPYTS FVKLLPLNDCRYALY DATYETKESKKEDLV FIFWAPESAPLKSKM IYASSKDAIKKKFTG IKHEWQVNGLDDIKD RSTLGEKLGGNVVVS LEGKPL |
| Sequence Similarities : | Belongs to the actin-binding proteins ADF family.Contains 1 ADF-H domain. |
| Gene Name : | CFL2 cofilin 2 (muscle) [ Homo sapiens ] |
| Official Symbol : | CFL2 |
| Synonyms : | CFL2; cofilin 2 (muscle); cofilin-2; |
| Gene ID : | 1073 |
| mRNA Refseq : | NM_001243645 |
| Protein Refseq : | NP_001230574 |
| MIM : | 601443 |
| Uniprot ID : | Q9Y281 |
| Chromosome Location : | 14q13.2 |
| Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; |
| Function : | actin binding; protein binding; |
◆ Recombinant Protein
| CFL2-1174H | Recombinant Human CFL2 Protein, GST-Tagged | +Inquiry |
| Cfl2-881M | Recombinant Mouse Cfl2 Protein, MYC/DDK-tagged | +Inquiry |
| CFL2-11143H | Recombinant Human CFL2, GST-tagged | +Inquiry |
| CFL2-26779TH | Recombinant Human CFL2 | +Inquiry |
| CFL2-11722Z | Recombinant Zebrafish CFL2 | +Inquiry |
|
|
◆ Lysates
| CFL2-7554HCL | Recombinant Human CFL2 293 Cell Lysate | +Inquiry |
|
|
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy
