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Recombinant Human CLIC4, His-tagged

Cat.No. : CLIC4-27273TH
Product Overview : Recombinant full length Human CLIC4 with an N terminal His tag; 273 amino acids with a predicted MWt 30.9 kDa including tag.
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Description : Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Protein length : 253 amino acids
Conjugation : HIS
Molecular Weight : 30.900kDa inclusive of tags
Source : E. coli
Tissue specificity : Detected in epithelial cells from colon, esophagus and kidney (at protein level). Expression is prominent in heart, kidney, placenta and skeletal muscle.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLVPRGSHMALSM PLNGLKEEDKEPLIELFVKAGSDGE SIGNCPFSQRLFMILWLKGVVFSVT TVDLKRKPADLQNLAPGTHPPFITF NSEVKTDVNKIEEFLEEVLCPPKYL KLSPKHPESNTAGMDIFAKFSAYIK NSRPEANEALERGLLKTLQKLDEYL NSPLPDEIDENSMEDIKFSTRKFLD GNEMTLADCNLLPKLHIVKVVAKKY RNFDIPKEMTGIWRYLTNAYSRDEF TNTCPSDKEVEIAYSDVAKRLTK
Sequence Similarities : Belongs to the chloride channel CLIC family.Contains 1 GST C-terminal domain.
Gene Name : CLIC4 chloride intracellular channel 4 [ Homo sapiens ]
Official Symbol : CLIC4
Synonyms : CLIC4; chloride intracellular channel 4; chloride intracellular channel protein 4; CLIC4L; DKFZP566G223; H1; huH1; p64H1; P64H1;
Gene ID : 25932
mRNA Refseq : NM_013943
Protein Refseq : NP_039234
MIM : 606536
Uniprot ID : Q9Y696
Chromosome Location : 1p
Function : chloride channel activity; protein binding; voltage-gated chloride channel activity; voltage-gated ion channel activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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