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Recombinant Human CPT1A

Cat.No. : CPT1A-26794TH
Product Overview : Recombinant fragment corresponding to amino acids 461-550 of Human CPT1A with an N terminal proprietary tag; Predicted MWt 35.53 kDa.
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  • Gene Information
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Description : The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein length : 90 amino acids
Molecular Weight : 35.530kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Strong expression in kidney and heart, and lower in liver and skeletal muscle.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : VFKNGKMGLNAEHSWADAPIVAHLW EYVMSIDSLQLGYAEDGHCKGDINP NIPYPTRLQWDIPGECQEVIETSLN TANLLANDVDFHSFP
Sequence Similarities : Belongs to the carnitine/choline acetyltransferase family.
Gene Name : CPT1A carnitine palmitoyltransferase 1A (liver) [ Homo sapiens ]
Official Symbol : CPT1A
Synonyms : CPT1A; carnitine palmitoyltransferase 1A (liver); CPT1; carnitine O-palmitoyltransferase 1, liver isoform; CPT1 L; L CPT1;
Gene ID : 1374
mRNA Refseq : NM_001031847
Protein Refseq : NP_001027017
MIM : 600528
Uniprot ID : P50416
Chromosome Location : 11q13.2
Pathway : AMPK signaling, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem;
Function : carnitine O-palmitoyltransferase activity; identical protein binding; transferase activity, transferring acyl groups;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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