Recombinant Human CPT1A
Cat.No. : | CPT1A-26794TH |
Product Overview : | Recombinant fragment corresponding to amino acids 461-550 of Human CPT1A with an N terminal proprietary tag; Predicted MWt 35.53 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Protein length : | 90 amino acids |
Molecular Weight : | 35.530kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Strong expression in kidney and heart, and lower in liver and skeletal muscle. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | VFKNGKMGLNAEHSWADAPIVAHLW EYVMSIDSLQLGYAEDGHCKGDINP NIPYPTRLQWDIPGECQEVIETSLN TANLLANDVDFHSFP |
Sequence Similarities : | Belongs to the carnitine/choline acetyltransferase family. |
Gene Name : | CPT1A carnitine palmitoyltransferase 1A (liver) [ Homo sapiens ] |
Official Symbol : | CPT1A |
Synonyms : | CPT1A; carnitine palmitoyltransferase 1A (liver); CPT1; carnitine O-palmitoyltransferase 1, liver isoform; CPT1 L; L CPT1; |
Gene ID : | 1374 |
mRNA Refseq : | NM_001031847 |
Protein Refseq : | NP_001027017 |
MIM : | 600528 |
Uniprot ID : | P50416 |
Chromosome Location : | 11q13.2 |
Pathway : | AMPK signaling, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem; |
Function : | carnitine O-palmitoyltransferase activity; identical protein binding; transferase activity, transferring acyl groups; |
Products Types
◆ Recombinant Protein | ||
CPT1A-02H | Recombinant Human CPT1A Protein, Myc/DDK-tagged | +Inquiry |
Cpt1a-936M | Recombinant Mouse Cpt1a Protein, MYC/DDK-tagged | +Inquiry |
CPT1A-1946M | Recombinant Mouse CPT1A Protein, His (Fc)-Avi-tagged | +Inquiry |
CPT1A-1817H | Recombinant Human CPT1A Protein, GST-tagged | +Inquiry |
CPT1A-1234R | Recombinant Rat CPT1A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CPT1A-7300HCL | Recombinant Human CPT1A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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