Recombinant Human CRYGC
Cat.No. : | CRYGC-27305TH |
Product Overview : | Recombinant fragment of Human gamma C Crystallin with N-terminal proprietary tag. Predicted MW 36.63 kDa. |
- Specification
- Gene Information
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Description : | Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | SIRSCCLIPQTVSHRLRLYEREDHK GLMMELSEDCPSIQDRFHLSEIRSL HVLEGCWVLYELPNYRGRQYLLRPQ EYRRCQDWGAMDAKAGSLRRVVDLY |
Sequence Similarities : | Belongs to the beta/gamma-crystallin family.Contains 4 beta/gamma crystallin Greek key domains. |
Gene Name : | CRYGC crystallin, gamma C [ Homo sapiens ] |
Official Symbol : | CRYGC |
Synonyms : | CRYGC; crystallin, gamma C; CRYG3; gamma-crystallin C; |
Gene ID : | 1420 |
mRNA Refseq : | NM_020989 |
Protein Refseq : | NP_066269 |
Uniprot ID : | P07315 |
Chromosome Location : | 2q33-q35 |
Function : | protein binding; structural constituent of eye lens; |
Products Types
◆ Recombinant Protein | ||
CRYGC-1939H | Recombinant Human CRYGC Protein, GST-tagged | +Inquiry |
CRYGC-869R | Recombinant Rhesus Macaque CRYGC Protein, His (Fc)-Avi-tagged | +Inquiry |
CRYGC-1276R | Recombinant Rat CRYGC Protein, His (Fc)-Avi-tagged | +Inquiry |
CRYGC-1044R | Recombinant Rhesus monkey CRYGC Protein, His-tagged | +Inquiry |
CRYGC-11605H | Recombinant Human CRYGC, His-tagged | +Inquiry |
◆ Lysates | ||
CRYGC-7258HCL | Recombinant Human CRYGC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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