Recombinant Human CSNK1A1

• Cat.No.: CSNK1A1-26814TH
• Product Overview: Recombinant full length Human Caseine Kinase 1 alpha protein expressed in baculovirus sf9 insect cells using an N terminal proprietary tag. Predicted MWt 62 kDa including tag

Specification

• Description: Casein kinase I isoform alpha is an enzyme that in humans is encoded by the CSNK1A1 gene.
• Protein length: 337 amino acids
• Molecular Weight: 62.000kDa inclusive of tags
• Source: Baculovirus infected sf9 cells
• Biological activity: Specific activity is 120 nmol/min/mg
• Form: Liquid
• Purity: Densitometry
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.Contains 1 protein kinase domain.

Gene Information

• Gene Name: CSNK1A1 casein kinase 1, alpha 1 [ Homo sapiens ]
• Official Symbol: CSNK1A1
• Synonyms: CSNK1A1; casein kinase 1, alpha 1; casein kinase I isoform alpha; CK1
• Gene ID: 1452
• mRNA Refseq: NM_001025105
• Protein Refseq: NP_001020276
• MIM: 600505
• Uniprot ID: P48729
• Chromosome Location: 5q32
• Pathway: Beta-catenin phosphorylation cascade, organism-specific biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Degradation of beta-catenin by the destruction complex, organism-specific biosystem; FoxO family signaling, organism-specific biosystem; Hedgehog signaling events mediated by Gli proteins, organism-specific biosystem
• Function: ATP binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity