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Native Human CTSS

Cat.No.: CTSS-27405TH
Product Overview: Full length native Human Cathepsin S purified from Human Spleen; amino acids 115-331, 217 amino acids, MWt 24 kDa.
Description: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Biological activity: Activity: Cathepsin S activity detected using Z-Val-Val-Arg-AMC
Form: Lyophilised
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 100mM Sodium acetate, 1mM EDTA, pH 5.5
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Gene Name: CTSS cathepsin S [ Homo sapiens ]
Official Symbol: CTSS
Synonyms: CTSS; cathepsin S;
Gene ID: 1520
mRNA Refseq: NM_001199739
Protein Refseq: NP_001186668
MIM: 116845
Uniprot ID: P25774
Chromosome Location: 1q21
Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing &
Function: cysteine-type endopeptidase activity; peptidase activity;

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